61.   In agreement with previous studies, we found that gastric metaplasia was significantly more prevalent in patients with duodenal ulcer disease than in patients with functional dyspepsia.

62.   After eradication of H pylori, duodenal ulcers do not usually recur and the associated chronic gastritis gradually disappears.

63.   This study suggests that both acid induced injury and H pylori infection may play a part in the pathogenesis of duodenal ulcer disease.

64.   Endoscopy in the nine H pylori positive non-uraemic patients showed oesophagitis in one patient and active duodenal ulcer in another.

65.   Eight healthy volunteers considered free from peptic ulcer disease and eight patients with endoscopically proved duodenal ulcer disease were studied.

66.   All subjects studied were regular smokers but the duodenal ulcer patients were significantly older and had therefore smoked for a longer period.

67.   In both controls and duodenal ulcer subjects the plateau of pyloric loss was not as stable as that of Vg.

68.   Acute cigarette smoking has been shown to reduce Vg significantly in controls and duodenal ulcer subjects.

69.   The authors concluded that increased antral gastrin is important in the pathogenesis of an increased maximal acid output in smokers with a duodenal ulcer.

70.   Previous studies have shown a remarkable morphological and behavioural similarity to duodenal ulcer in man.