41.   It would mark a wholesale change, reminiscent of when pasteurizing milk became the law of the land early last century.

42.   Many in the NHL are expecting Dudley to make wholesale changes on the coaching staff.

43.   Many Republicans are strongly opposed to wholesale changes in the law.

44.   Now Vick has made wholesale changes, more than enough to warrant a second look.

45.   Of course, before you make this or any other wholesale dietary change, consult your doctor.

46.   Now, at last, has come a season of wholesale change and success.

47.   Of course, a January list can undergo wholesale changes by June.

48.   Other defensive players pinpointed specific offensive players and added that coach Jim Fassel should make wholesale changes if needed.

49.   Or maybe it was when Giants Coach Jim Fassel finally caved in, turning his sideline into a fire drill as he made wholesale changes in the offensive lineup.

50.   Other tobacco industry concessions will bring wholesale changes to the way tobacco products are marketed and sold.