41.   Tighter regulations, higher taxes and frequent fines forced many companies out of business and drove others to seek a more welcoming climate elsewhere.

42.   Tighter regulation of derivatives, Miller says, would probably do more harm than good, particularly if it came from the Commodity Futures Trading Commission.

43.   Tighter banking regulations, currency risks and volatile markets have led some trade banks to play with creative financing.

44.   Top U.S. officials have repeatedly urged Mexico to control money laundering through tighter regulation.

45.   Tighter regulations, better winemaking and plain old competition have all contributed to transforming Chianti from a hearty peasant vino into a world-class wine.

46.   Treasury officials say the figure will decrease over time because of tighter regulations created under the Clinton administration.

47.   To them, his call for tighter regulations within the watershed threatens the economic growth of their region.

48.   With the uptick in gene therapy trials, the government continues to impose tighter regulations.

49.   A shift by Germany, until now a staunch opponent of new rules on tobacco advertising, would add a decisive vote in favor of tighter regulation.

50.   Although tighter regulations on canyoning will likely be considered, there are no immediate plans for a clampdown on that or other extreme sports.