41.   Assist pumps were first developed as a temporary measure to keep people with advanced heart failure or other severe cardiac problems alive while they waited for heart transplants.

42.   As with many American orchestras, its existence has recently been threatened by severe financial problems.

43.   Asthma is a chronic, inflammatory lung disease that clogs the breathing tubes, causing mild to severe breathing problems.

44.   Attorneys for Harris, describing him as a man with severe psychological problems and an addiction to alcohol and cocaine, had pressed jurors to spare his life.

45.   Because of a severe respiratory problem, he often vomited and endured frenzied coughing spells in the middle of the night.

46.   Bertrand said Monday that boats such as One Australia are like grand prix racing cars that occasionally have severe problems.

47.   A feather-like algae that has caused severe ecological problems in the northwestern Mediterranean has been found for the first time off the West Coast of the Americas.

48.   A few utilities have faced such severe problems with nuclear plants that they have decided to shut the plants permanently, a costly and lengthy process.

49.   A second problem is that he seems to lump all problems with immigrants together, when it would seem that the most severe problems come from illegal immigrants.