41.   The most serious setback is a California-style energy crisis that has forced the government to ration electricity.

42.   The Nets Inc. bankruptcy marks a serious setback for Manzi, a former newspaper reporter who rose to become chairman of Lotus.

43.   The New York Knicks have suffered their first serious setback of the season.

44.   The Pentagon suffered a serious setback in January when a missile fired from the Marshall Islands failed to hit a mock warhead fired from a California air base.

45.   The school voucher movement suffered a serious setback with the overwhelming defeat of voucher initiatives in California and Michigan.

46.   The ruling is the second serious setback for aggressive judges in recent months and could dampen what some critics have said is an excess of judiciary zeal these days.

47.   The serious setback likely leaves Autoimmune, of Lexington, Mass., years away from any profits.

48.   The results appeared to be a serious setback for the company.

49.   The threat poses a serious setback to the Conservative Party, whose majority in Parliament is expected to be reduced to one after a local election next week.

50.   The Social Democratic Party has suffered serious setbacks since the spring in local elections and in the voting for the European Parliament.