31.   Regulation also causes big headaches.

32.   Rice is beginning to remind people of a big headache.

33.   Selling wine over the Internet can give wineries one big headache, especially if the buyer is underage.

34.   Sounds like a big headache, right?

35.   That could pose big administrative headaches and interfere with companywide efforts to rein in health care costs.

36.   That list of clients was a big headache for American officials hoping to stem the spread of nuclear weapons.

37.   The dramatic shift in power, which promised big headaches for Clinton, also brought big changes to the Texas congressional delegation.

38.   The high cost of staying is a big headache for business travelers and students who come to Japan for study.

39.   The Odyssey is a prime example of how a single successful product can cause big headaches in Detroit.

40.   They have become a big headache for the NATO-led peacekeepers here.