21. Subjects with adenomatous polyps and cancer have an increased cell proliferation and a shift of the proliferative zone towards the apex of the crypt. 22. They found that supplementation reduced the total cell proliferation although in contrast with our results, vitamin C did not change the upward shift of the proliferative zone. 23. Cellular proliferation was increased in the proximal colon and there was a shift of proliferating cells to a higher region in each crypt. 24. This is reflected in a retained capacity for DNA synthesis which leads to an expansion or a shift of the proliferative compartment towards the upper portions of the crypt. 25. Our breathing work today is a direct outcome of this development and shift of emphasis. 26. Our data confirm an upward shift of the proliferative zone in the patients with adenomatous colorectal polyps. 27. The upwards shift of the proliferating compartment is not necessary for the development of adenomas buds, even in FAP cases. 28. For a monolingual speaker, it may mean a shift of style within what is perceived to be the same language. 29. This is not just a subtle shift of emphasis. 30. The laser-Doppler anemometer measures velocity by measuring the Doppler shift of light scattered within the moving fluid. |