21.   A new technique is making it possible to deliver higher doses of radiation to the prostate while sparing normal tissues.

22.   Additional studies are needed to evaluate the benefits of higher doses of Invirase with AZT, and other combinations of drugs, Hoffmann-La Roche officials said.

23.   All these benefits, however, have been attained with much higher doses of vitamin E than the diet normally supplies, so doctors are recommending supplemental vitamin E.

24.   But higher doses of vitamin E can interfere with blood clotting and may increase the risk of bleeding disorders and hemorrhagic stroke.

25.   But in its clinical trial, higher doses of Epogen were given to dialysis patients with severe heart disease.

26.   But the federally funded researchers warned that more study is needed to make sure immunized rats would not try to compensate by ingesting higher doses of cocaine.

27.   Clinical trials showed that the serious side effects occurred when patients were receiving higher dose.

28.   Clinical studies showed the drug was safe and effective, though some patients might need higher doses, the FDA said in a statement.

29.   Cold weather can cause a user to get little or no nicotine per puff while warmer weather can cause higher doses, the company said.

30.   Curiously, though, higher doses did not work.