21.   Methotrexate, a key drug for rheumatoid arthritis, could help people with the crippling disease live longer, new research suggests.

22.   Polio, a crippling disease spread by a virus paralyzed thousands of children in South Asia.

23.   Tens of thousands of health officials and volunteers Saturday began administering polio vaccine to children across this vast nation that remains the last stronghold of the crippling disease.

24.   The crippling disease is contracted by drinking water contaminated with the worm larvae.

25.   WHO and UNICEF sent the appeal to countries still afflicted by the crippling disease.

26.   But when a normal prion mutates, it destroys brain nerve systems and causes crippling diseases, including mad cow disease.

27.   The young Islamic scholar has become one of the most outspoken opponents of an internationally funded immunisation drive launched to wipe our remaining pockets of the crippling disease.

28.   Nigeria and Niger will this week embark on a cross-border polio immunisation programme as the world enters the endgame of its duel with the crippling disease.

29.   The anti-polio drive will be followed up in the next two years by further mass immunisation days in an attempt to ensure the eradication of the crippling disease.