11.   Significant excretion of solute-free water can not occur unless significant amounts of solute and water reach this point.

12.   The presence of significant amounts of haemoglobin F has a protective effect against sickling and such individuals express relatively mild disease.

13.   This can be a significant amount, which May offset many of the advantages of leasing.

14.   To win a significant amount of new business would require a big cultural change at the company.

15.   We should reclaim our leadership position by immediately sending a significant amount of food aid.

16.   Without a significant amount of public ownership therefore, a liberal Market system gives companies independence.

17.   ...foods that offer a significant amount of protein.

18.   He won a significant amount of money.

19.   The store has lost a significant amount of business since the factory closed.

20.   Since it is known that Japanese manufacturing companies in general often subcontract a significant amount of their production, the last ratio should not be taken seriously.