11.   Seven patients suffered from melaena alone.

12.   In this series one patient suffered a bowel perforation as a result of an endoscopic biopsy that was done to check response to the gluten free diet.

13.   One patient suffered with transitory lethargy during treatment, which may have been related to radiotherapy.

14.   One patient had suffered grade three frostbite and had had both feet amputated.

15.   She vowed if it was humanly possible, no other patient would suffer a similar fate through lack of a suitable donor.

16.   And because of the dearth of good options, many patients have been suffering for years.

17.   And patients would suffer because the shortage of doctors would just get worse.

18.   Another is that such advance directives are usually too vague to be of much use when patients are suffering.

19.   Another unidentified patient suffered serious cardiac injury but survived.

20.   Because they lack the crucial blood-clotting factor, the patients suffer from dangerous spontaneous bleeding.