11. Our data indicate an association between the genetic polymorphism at the PGC gene locus and gastric body ulcer. 12. The allele frequency of the small fragment of the PGC RFLP in patients with gastric body ulcer was significantly hgiher than that in controls. 13. The genotypes containing the small fragment were significantly more frequent in patients with gastric body ulcer than in controls and in patients with gastric angular or antral ulcer. 14. These results suggest that the PGC RFLP is a useful subclinical marker of the genetic predisposition to gastric body ulcer. 15. The allele frequency of the small fragment of the PGC RFLP was significantly higher in patients with gastric body ulcer than in patients with gastric angular or antral ulcer. 16. One is that the PGC gene itself is one of the genes responsible for gastric body ulcer. 17. The racial difference of the association between genetic polymorphisms of PGC and gastric body ulcer remains unclear in this study. |