11.   The caecal and colonic tissue weights were significantly higher in the rats fed the higher fibre diet than those fed the low fibre diet.

12.   The higher fibre diet fed to the rats could be regarded as their normal fibre intake and thus this study compared normal fibre intake with low fibre intake.

13.   This may also be said of the fibre intake in man where we generally eat a low fibre diet but evolved eating a high fibre diet.

14.   Conversely, a low fibre diet did not lead to changes in cellular proliferation which might be associated with mucosal instability.

15.   Two further patients could not tolerate the high fibre diet and the remaining three defaulted for no apparent reason.