11.   OxyContin abuse first became widespread in mountainous areas of Kentucky, West Virginia, Virginia, Tennessee and Maine.

12.   Amphetamine abuse has become a major problem in Thailand, with some drug officials saying it is a bigger threat than heroin.

13.   Drug abuse had become a problem in every large town in the country, he said, without giving precise figures.

14.   Incredulous commissioners tried to pin Vlok down, saying it was hard to understand how abuses became so systemic.

15.   The raw ingredients are usually smuggled in from China, and the finished product is marketed in Thailand, where methamphetamine abuse has become a plague.

16.   They said it was hard to understand how human rights abuses became so systemic.

17.   While heroin remained at the top of the list, ice abuse has become a new concern for the bureau, he said.

18.   Drug abuse has become an increasing problem in recent years as Indonesia moves from being a mere transit point on international drug smuggling routes to a market.