101.   The cancer had spread to her spine and neck.

102.   The cancer has spread to the bones of her leg and a single area inside her brain, York said.

103.   The cancer spread, and Mrs. Makino died.

104.   The cancer had spread to his chest and probably his liver.

105.   The cancer had spread to his lungs and abdomen and even to his brain.

106.   The cancer spread into her lymph nodes.

107.   The cancer spread throughout his body, including his lymph nodes and liver.

108.   The combination was administered to women whose breast cancer had spread to other organs and failed to respond to conventional drugs.

109.   The gene therapy would be a significant development for men whose prostate cancer has spread so far beyond the gland that it is impossible to remove through surgery.

110.   The nodules on his lung suggested the cancer had spread and might continue until it killed him.