1.   Chronic idiopathic constipation, however, is often associated with other motility disturbances involving multiple organs, suggesting an underlying systemic disease of the autonomic nervous system.

2.   Primary chronic intestinal pseudo-obstruction occurs without underlying systemic disease.

3.   While examining the patient, it is important to look for signs of systemic disease such as telangiectasia, signs of chronic liver disease or purpura.

4.   They may be appropriate, however, in patients where the history or examination points to systemic disease such as chronic liver disease.

5.   Amyloidosis is a systemic disease of unknown cause in which damage to the heart and other organs results from deposits of the protein amyloid.

6.   A court-appointed panel of experts has concluded that existing scientific evidence does not show a link between silicone breast implants and systemic disease.

7.   But the report asserts in forceful terms that there is no reason to believe that the implants cause rheumatoid arthritis, lupus, or any other systemic disease.

8.   He specializes in breath studies to diagnose systemic diseases.

9.   However, the FDA did not find that the implants were causing systemic disease.

10.   Since there was still no good evidence that silicone caused systemic disease, critics called this court-sanctioned robbery.