1.   A further eight patients with villous adenomas but no evidence of malignant change were deemed unsuitable for the study and were given laser treatment only.

2.   Eleven of these patients had rectal or rectosigmoid adebicarcinoma, one had direct rectal invasion from cervical cancer, and one an extensive villous adenoma.

3.   Twelve colonic adenoma biopsy specimens were examined, of which six were tubular adenomas, three were villous adenomas, and three were tubulovillous adenomas.

4.   In areas of villous adenoma some of the tumour cells also showed nuclear immunoreactivity.