1.   Any woman whose mother took this hormone while pregnant is at increased risk for a rare vaginal cancer, infertility and other medical problems.

2.   But none of the Pap tests or follow-up biopsies found vaginal cancer.

3.   Later, it was found to cause genital abnormalities and a rare form of vaginal cancer in women exposed to it while in the womb.

4.   Newbold reported last year that granddaughters of treated female mice have significantly higher-than-normal incidence of vaginal cancer.

5.   Their daughters, doctors learned later, suffered from reduced fertility, immune system disorders and vaginal cancers.

6.   There is some evidence for a DES-related testicular cancer that is biologically related to the vaginal cancer found in DES daughters.