1.   Numerous episodes of pilferage, taken in the aggregate, can really add up to a significant sum.

2.   The committee noted that although significant sums had been invested in rural hospitals, those still relied heavily on local GPs and larger district general hospitals.

3.   Like everyone else, ICI was losing significant sums of money on petrochemicals and we had to take a very hard look indeed at where we were going.

4.   And why would out-of-staters donate significant sums to Pataki?

5.   As a result, the city could have to surrender some control over the LAPD and be required to spend significant sums on specified programs.

6.   A professor makes a venture bet, risking a significant sum in hopes of boosting a lackluster nest egg.

7.   But if you ignore the complexities and ambiguities of pricing, you may end up leaving significant sums of money on the table.

8.   Furniture, folk art, silver, porcelains, historical documents and American Indian art changed hands, often for significant sums.

9.   Gore would spend more than Bush on education and health care, and he would devote significant sums to paying down the national debt.

10.   He said it is not clear how much the immigrants were being charged for the licenses, but it appears to have been a significant sum.