1.   The company said that it would result in a significant loss for the year.

2.   A map of the topography of the coastline shows a significant loss of wetlands.

3.   The bid-ask spread was so large that it converted significant profits into significant losses.

4.   No significant loss of cell viability resulted from pretreatment as judged by trypan blue exclusion tests.

5.   Any loss of genetic material in an endangered species with such a limited range and such a small population is a significant loss.

6.   The Association of British Independent Oil Companies claimed a significant loss of jobs would result from the adjustments which were introduced in the Budget without industry consultation.

7.   Insider trading may also lead to a significant loss of confidence in the Stock Exchange, particularly amongst small investors.

8.   American insurers, with a few exceptions such as the American International Group, do not have enough business in Japan to face significant losses from the earthquake there.

9.   Among the significant losses are access to information, the right to appeal and a jury of peers.