1.   Several widely used non-steroidal anti-inflammatory drugs have been reported as causing severe hepatitis.

2.   Three cases of severe acute hepatitis have been reported in association with piroxicam.

3.   Although changes in liver function tests are very rare, three cases of severe acute hepatitis secondary to piroxicam have been reported.

4.   One had severe acute alcoholic hepatitis and had continued to drink despite medical advice to the contrary.

5.   Severe acute hepatitis immediately after intravenous amiodarone has been reported four times.

6.   A new two-drug treatment designed to prevent tuberculosis has resulted in at least two cases of severe hepatitis, including one death.