1.   In particular, the frequency of the dose should be reduced in patients with renal impairment, including elderly people.

2.   We could demonstrate that cGMP yields high sensitivity and specificity for cardiac diseases in the absence of severe renal functional impairment.

3.   To correct for the wide range of renal impairment in the patients studied, the ratios of carbamylated haemoglobin with both serum urea and creatinine concentrations were calculated.

4.   Severe potassium depletion is associated with muscular weakness, cardiac arrhythmias, and renal impairment, but over vigorous replacement poses dangers and potassium is best given orally.