1. Patients receiving sulphasalazine at study entry continued to take the drug throughout the study and did not reduce the dose. 2. Only one patient receiving cyclosporin met our criteria for nephrotoxicity and that patient improved after reducing the dose. 3. Every time Upjohn denied the safety concerns yet subsequently reduced the dose. 4. Griffin said it took her own initiative for the clinic to start reducing her dose a milligram or two a week in pursuit of getting off. 5. Grady suggested a more gradual tapering of the dose than Mrs. W. had tried, perhaps reducing the dose one day a week and then proceeding slowly. 6. The most important is to talk to your doctor about reducing the dose. 7. Neudorf wanted to reduce the dose for a test on children in full relapse. 8. Six stopped taking Mirapex and two others reduced the dose, and the sleep attacks stopped. 9. With so many victims, doctors have had to reduce normal doses of medicines, he said. |