1.   In this study the efficacy of adsorbents as antiendotoxin agents in a hapten induced rat model of colitis is investigated.

2.   Bile acids given either orally, or rectally, have been shown to have a tumour promoting effect in rat models for colorectal cancer.

3.   Evidence supportive of this mechanism is that vitamin E, a fat soluble free radical scavenger, reduces the formation of fluid in a rat model of radiation enteritis.

4.   This phenomenon has been reproduced in a rat model of ethanol feeding and subsequent lipid analyses indicated that accumulated cholesteryl esters were responsible for the morphologic changes observed.

5.   Ketotifen, a drug used for the prevention of asthma, was found to decrease significantly the extent and severity of experimental colitis in two rat models.

6.   In the rat model, operations that lead to duodenogastric reflux give a higher yield of gastric tumours in animals dosed with carcinogen.