1. Nuclei were isolated from cell lines or spleen from transgenic animals or inbred mouse strains. 2. In previous work, using Ea transgenic mice or recombinant mice strains, the presence of AbetaE mixed isotype molecules at the cell surface was shown. 3. A vaccine that would normally protect mouse strains that are susceptible to the virus only worked in half the mice exposed to the killer version. 4. But if they give the same gene to another mouse strain, called kayliss, the mice not only grow fat but are dead of diabetes in five months. 5. Scientists long ago discovered two mouse strains that were interesting because they were small. 6. Since the leptin gene discovery, scientists have found a number of other mouse strains with gene mutations affecting their weight and energy balance. 7. That year, Little developed the first inbred mouse strain by mating brothers and sisters. 8. The new mouse strain does not open the door to geriatric motherhood, possibly because the aged animals lack the pituitary hormones necessary to sustain pregnancy. 9. One mouse strain had the normal Fas protein while the other mouse type lacked the protein. |