1.   Although the science of locating genes is well in place, linking the genes to the sole cause of disease has not been well established.

2.   By focusing on a family, researchers can locate similar genes and accelerate and streamline the design process.

3.   By isolating specimens whose internal clocks were out of sync, scientists were able to locate the genes that control biological rhythms by identifying genetic variations.

4.   Dr. Joel F. Habener, director of molecular endocrinology at Massachusetts General Hospital, has located six genes involved in a common form of diabetes.

5.   Last year other researchers located genes that make some women extraordinarily prone to breast and ovarian cancer.

6.   Researchers could locate certain genes with respect to these landmarks, thereby putting the genes on a map.

7.   Researchers have located migraine genes in different families that have strong headache histories.

8.   Scientists liken them to signposts or bookmarks, because they serve as reference points in uncharted regions of DNA, landmarks to help biologists locate genes they are hunting.

9.   Scientists located a gene that regulates how fast the body burns calories.

10.   Since then, said Tanzi and others, a number of laboratories had raced to locate the gene and decipher its chemical message.