1.   The handling of PT-gliadin by the intestinal epithelium in coeliac patients in remission and control individuals was investigated by in vivo instillation of PT-gliadin.

2.   Furthermore, the results are in agreement with the suggestion of a functional alteration in the zonula occludens in the intestinal epithelium of coeliac patients.

3.   Our results support the hypothesis of a functional alteration in the zonula occludens in the intestinal epithelium of coeliac patients.

4.   In intestinal epithelium, cyclic nucleotides are involved in the regulation of water and electrolyte transport and mediate the action of various hormones, prostaglandins, and bacterial enterotoxins.

5.   The three main groups of glutathione S-transferases are,, and, mainly present in the liver, but also present in various extrahepatic tissues including intestinal epithelium.