1.   The discovery Marks a significant technological advance.

2.   The discovery marks a clear advance in understanding the basic biology of the virus.

3.   The discovery marks a clear advance in understanding the basic biology of the virus, knowledge that may open up new approaches to research and treatment.

4.   The discovery marked the disastrous end of what had been a fairly standard separation.

5.   The discovery marked the first real victory for recovery crews since the aircraft nosedived into a desolate expanse of the Florida Everglades two days ago.

6.   Their discovery marks the first time circadian rhythm genes have been implicated in a behavioral disorder.

7.   Melnick said the discovery marks the first time a solar-system type of water cloud has been found around a star other than the sun.

8.   The discovery marked the first time this year that the potentially deadly virus has been found in mosquitoes in New York City.

9.   The discovery marks the first time the disease has been found in a Dutch herd.

10.   The Wulongsong discovery marks first known case of blood product contamination in China.