1.   The high cost of capital has a crippling effect on many small American high-tech firms.

2.   According to Richard Porter, RSPB head of species management, deliberate persecution has had a crippling effect on some of our rarest birds of prey.

3.   But they said it would undercut arguments by Philip Morris and RJ Reynolds that disclosure would have a crippling effect.

4.   Carolyn McCarthy knows the crippling effect of crime better than anyone.

5.   Even more important, arguably, was that Watson accurately portray the crippling effects of multiple sclerosis.

6.   Few said they expect the threat to be carried out, because of its crippling effect on agriculture.

7.   In his day, Roosevelt did not feel the need to hide his smoking habit, but went to great lengths to conceal the crippling effects of his polio.

8.   Many, of course, will point to the crippling effects of the publicity surrounding the Ford Explorer debacle.

9.   Rather, Sebald focuses on the crippling effects of the past.

10.   Related studies show that exercise increases bone density, which helps prevent the crippling effects of osteoporosis.