1.   Although the human genome is a gold mine in principle, it is unclear exactly where the commercial payoff will come.

2.   But last week, this crusade by Brewster Kahle had a big commercial payoff.

3.   He said such knowledge resulted from considerable money and effort, which would not be expended without the lure of a commercial payoff.

4.   Other national crises have had a huge commercial payoff.

5.   So-called basic research is by definition far removed from immediate applications and commercial payoffs.

6.   This has become painfully obvious to those expecting a commercial payoff from the Internet.

7.   With the human genome data, there are much higher stakes in terms of intellectual credit for a landmark achievement and the prospect of a huge commercial payoff.