1.   Invitro, high extracellular calcium concentrations inhibit the proliferation of human colonic epithelial cells and several colonic cancer cell lines.

2.   Two early studies showed an increased faecal bile acid excretion in patients with colonic cancer, but later studies have been unable to confirm this.

3.   Stronger evidence provided by in vitro studies has confirmed the link between vitamins A, E, C, and Beta -carotene and colonic cancer.

4.   The coexistence of colonic cancer or large polyps with an upper gastrointestinal lesion identified at endoscopy was rate in outpatients referred from family practitioners.

5.   The patients we identified with colonic cancer were in the older age range of our group with ages comparable with studies with higher incidences of cancer.

6.   Few reports, however, have shown the relation between HPV and colonic cancers.

7.   In conclusion, the HPV DNA of colonic cancer cells can integrate and induce neogrowth in mouse cells.

8.   This study provides valuable insight into the association of HPV DNA with colonic cancers.

9.   In vitro, high extracellular calcium concentrations inhibit the proliferation of human colonic epithelial cells and several colonic cancer cell lines.