1.   Big changes were in the offing.

2.   But if the revolution in microelectronics is not yet faltering, there are signs of two big changes.

3.   Going to a new school is a big change for children.

4.   I saw a big change in her when I met her again.

5.   It takes courage to make a big change in your life like that.

6.   Making big changes in your diet all at once is a bad thing to do.

7.   So these older workers have been immune to big changes in work-related phenomena.

8.   There have been big changes in the way languages are taught in schools.

9.   There will be some big changes in the way we work.

10.   To win a significant amount of new business would require a big cultural change at the company.