1.   Amyloidosis occurs when an abnormal protein becomes fibrous and becomes deposited in the heart muscle.

2.   The abnormal proteins produced by these degenerative diseases are relatively indigestible, so they build up in the lysosome.

3.   These degenerative diseases - spongiform encephalopathies - have been linked to the production of abnormal proteins in the brain.

4.   Another highly promising approach to have grown out of immunopathology and molecular pathology is the development and use of tumor vaccines to attack the abnormal proteins in cancer cells.

5.   Attention seems to be centering on abnormal proteins, but disagreement remains.

6.   A hallmark of the disease is that dopamine cells in the substantia nigra become clogged with tiny, gunky clumps of abnormal protein called Lewy bodies.

7.   A normal gene makes a normal protein and a diseased gene presumably makes an abnormal protein.

8.   His doctors said he also had amyloidosis, which causes the liver to produce an abnormal protein that attacks body organs.

9.   One defective gene produces one abnormal protein that results in a disease.

10.   Researchers have an idea of how these abnormal proteins gum up brain cells, Housman said.