71.   The agency plans to send warning letters to individuals running chain letter operations.

72.   The anonymous warning letter to Lay was written by Sherron S. Watkins, a vice president of corporate development, according to several people who knew of the letter.

73.   The discovery of the risk was uncovered by researchers at the Mayo Clinic and prompted the Food and Drug Administration to send warning letters to thousands of doctors.

74.   The FDA expressed its concerns about the misleading information the company gave to doctors about the drug in a harshly worded warning letter in September.

75.   The FDA issues hundreds of warning letters every year, but only a small minority result in agency action.

76.   The FDA sends hundreds of warning letters to companies each year and only a few of them result in substantial agency action.

77.   The FDA sends hundreds of warning letters to companies each year and only a small minority of them result in any significant agency action.

78.   The FDA sends hundreds of warning letters to companies each year and only a small minority of them result in any substantive agency action.

79.   The FDA sends hundreds of warning letters to companies each year and only a small minority of them result in substantive agency action.

80.   The FDA warning letter noted that a similar, unapproved refiltration occurred during the making of a batch of Activase.