71.   Only one drug, Biaxin, is approved for the disease, but many patients develop resistance to it.

72.   Other outbreaks have been blamed on bacteria developing resistance to antibiotics.

73.   One reason scientists are hesitant to proclaim victory over HIV is that it has a tremendous capacity to mutate, causing patients to develop resistance to drugs.

74.   Plasmodium goes through stages of development in its host species and this, with its ability to develop drug resistance, has made it hard to combat.

75.   Pests have developed resistance to chemicals.

76.   Public health officials blame overuse and inappropriate use of antibiotics for the steady increase in bacterial imperviousness, but they also note that germs naturally develop resistance over time.

77.   Researchers are trying to sabotage this strategy to fight a devastating worldwide pest, the Colorado potato beetle, which has proved particularly adept at developing resistance to insecticides.

78.   Recently, Stanford University Medical Center researchers reported that for many AIDS patients treated with protease inhibitors, their bodies have developed resistance to the drugs.

79.   Researchers say they do not expect the mothers to develop resistance to AZT after ending a short course.

80.   Scientists at the Vancouver meeting theorized that it would be difficult for the AIDS virus to develop resistance to the new anti-virals.