61.   If you want to be a commodity, you must undergo a profound change in character for the better.

62.   In just a week, there have been so many profound changes across the California landscape that it is difficult to catalog them all.

63.   In some states, the courts have ordered profound changes.

64.   In the broadest sense, the threat to Microsoft is contained in what may be a profound change in the way people use their computers.

65.   In the process, they are bringing profound change to one of the most unusual outposts of American society.

66.   Indeed, the bill, which would make the most profound changes in welfare programs since the New Deal, faces serious obstacles in the Senate.

67.   Indeed, we are in the midst of profound change.

68.   Interviews with Kurds in Berlin and other European cities suggest that what Tuzun has seen reflects a profound change of direction for the cause of Kurdish nationalism.

69.   It exposed strained relations between the Saudis and the United States, and sparked profound changes in the way America protects the oil-rich desert kingdom.

70.   It is a profound change in the family structure that is swiftly becoming an epidemic.