51.   Frohnmayer, president of the University of Oregon, has already lost two daughters to a rare genetic disease called Fanconi anemia that causes the bone marrow to fail.

52.   Gehrig, well aware he was dying of a rare disease, had an admirable perspective on his situation.

53.   Government incentives for the study of rare diseases has helped spur the creation of the biotech industry, which has become an integral part of the Massachusetts economy.

54.   Government incentives such as the U.S. Orphan Drug Act have been crucial in stimulating the development of drugs for rare diseases in wealthy nations.

55.   He had volunteered for the trial to test the potential treatment for a rare liver disease.

56.   He became intrigued by two different cases of children with homocystinuria, a rare genetic disease in which the levels of homocysteine in the blood are unnaturally high.

57.   He has a rare disease.

58.   He never had to recover from a bullet wound or battle a rare tropical disease.

59.   He has been dying slowly for months, his body succumbing in stages to the rare genetic disease that one day soon will leave him unable to breathe.

60.   He was suffering from a rare disease that caused the bile ducts of his liver to become blocked.