41.   It also is developing a combination of the active ingredients in Prozac and its psychosis drug Zyprexa for hard-to-treat depressed patients.

42.   Its use has increased in recent years for intractably depressed patients who fail to respond to medication.

43.   Whichever, it does seem linked to a stress hormone called cortisol, because about half of seriously depressed patients secrete too much cortisol.

44.   Zarifian thinks doctors may prescribe freely because they get a lucrative cut from the pharmaceutical companies, or because they fear a lawsuit if a depressed patient commits suicide.