41.   And his biggest problem is Reed.

42.   And even that was not their biggest problem.

43.   And he admits that his biggest problem is public mistrust of the media in general.

44.   And right now, the biggest problem we have is revenue.

45.   And the biggest problem for me, the one that affects me the most, has been the tiredness.

46.   And the possibility of fund-raising violations by Gore, a matter still under the scrutiny of Attorney General Janet Reno, does not seem to be his biggest problem.

47.   And we have AIDS also, which is the biggest problem in Africa.

48.   And that is his biggest problem.

49.   And there were candid discussions of substance abuse, including an assertion by one official that alcohol abuse was the biggest problem among players.

50.   Arthur J. Alexander, president of the Japan Economic Institute, points out that the countries with the biggest problems share significant economic development philosophies.