41.   The amount of AAGPC was calculated as the difference between the concentrations of platelet activating factor measured after and before alkaline hydrolysis and acetylation.

42.   Given the various substances that can activate platelets, it was necessary to show that the platelet aggregating material purified from gastric juice samples was platelet activating factor.

43.   Platelet activating factor plays a part in the mucosal injury of the gastrointestinal tract in anomals.

44.   Until now, however, only a few data pointed to the production of platelet activating factor in physiological processes.

45.   The significance of platelet activating factor in the gastric juice of healthy humans is still difficult to analyse.

46.   We can not exclude the possibility, however, of abnormal metabolism of platelet activating factor in four of them.

47.   Thus, the role of platelet activating factor should be interpreted considering both H pylori and acid.

48.   The fact that pentagastrin increased platelet activating factor precursors would suggest that platelet activating factor may have a role in the gastric functions, in particular gastric acid secretion.

49.   Also Wallace and keenan have reported that intracolonic administration of platelet activating factor may have a protective role in the gastrointestinal tract in animals.

50.   As platelet activating factor was not detected under pentagastrin infusion, two hypotheses should be discussed concerning the effect of pentagastrin on gastric platelet activating factor synthesis.