31.   The FDA grants the designation to encourage drug development in cases where a disease affects few people, providing a small market opportunity.

32.   The market opportunities could be as large as trillions of dollars, he added.

33.   The market opportunity is huge.

34.   The new company would be publicly funded and free to purse other market opportunities worldwide on a fully commercial and competitive basis, Comsat said.

35.   The state had already been planning to sell bonds Thursday, but decided to issue even more debt when it sensed the market opportunity.

36.   The shortage may also mean delays in new products, missed market opportunities, and a loss of customers to competitors.

37.   The U.S made a surprise announcement last night that it would only open its markets to those countries who offer the same market opening opportunities to U.S. firms.

38.   They were aimed at much smaller market opportunities than the kinds of companies competing today.

39.   They help businesses flourish by providing access to venture capital, consultants and other market opportunities, he said.

40.   They need to be responsive to investors, to take advantage of a potentially huge market opportunity, and to head off the persistent problem of online music piracy.