31.   Similarly, Telor Ophthalmic Corp. of Woburn, Mass., which was also developing vision medicines, pulled the plug when its drug to treat glaucoma also failed.

32.   Standard practice for treating APL at Memorial is to first give retinoic acid and other chemotherapy and later arsenic if the first drugs fail.

33.   The available drugs have failed for many infected people, and a concern is that they may also fail among those newly infected with resistant HIV.

34.   The drug agency has approved Enbrel for use by people with moderate or severe arthritis for whom existing drugs have failed.

35.   The first two drugs he tried failed.

36.   The same drug had failed an earlier trial for graft versus host disease, a common complication of bone marrow transplants.

37.   The second, more likely scenario is that anti-HIV drugs either fail to block virus production completely or that the cells harboring the virus live indefinitely, he said.

38.   When biotech drugs fail in clinical trials, many companies simply close their doors.

39.   When drugs fail, the only options are open heart surgery or the new, nonsurgical procedure called septal ablation.

40.   Every drug failed.