21.   An enzyme deficiency provoked by a defective gene causes pycno, a rare disease that may have afflicted the French painter.

22.   On Friday Akihito and Michiko are to visit the historic city of Albi, north of Toulouse, famous as the birthplace of the French painter Henri Toulouse-Lautrec.

23.   On Friday, Akihito and Michiko are to visit the historic city of Albi, north of Toulouse, famous as the birthplace of the French painter Henri Toulouse-Lautrec.