11.   Among the putative mediators are reactive oxygen species.

12.   This study presents evidence, based on chemiluminescence data, that further suggests that reactive oxygen species play a part in ulcerative colitis.

13.   These three reactive oxygen species are believed to be responsible for tissue injury.

14.   This reaction has been implicated in the generation of reactive oxygen species in ischemic reperfusion injury, a mechanism which has been recently postulated for inflammatory bowel disease.

15.   It is postulated that the deleterious effect of these reactions and their products is, at least in part, through their ability to generate reactive oxygen species.

16.   This finding suggests that the cyclo-oxygenase pathway could be an important contributor to the production of reactive oxygen species in the inflamed mucosa.

17.   As indomethacin is also known to be an reactive oxygen species scavenger, however, its effect may be independent of its inhibition of cyclo-oxygenase.

18.   The known clinical benefit of leukotriene inhibitors in ulcerative colitis, however, could still be due to their ability to indirectly decrease tissue reactive oxygen species.

19.   Reactive oxygen species have a role in ischaemia-reperfusion injury of the intestine, and may also participate in the pathogenesis of several kinds of gastric lesions.

20.   The role of reactive oxygen species in ulcerative colitis has been studied by the use of circulating or isolated phagocytic cells of patients with this disease.