11.   The smallpox vaccine is being manufactured by Acambis, a British company.

12.   The vaccine was manufactured in a Lansing, Mich., laboratory originally owned by the Michigan State Health Department.

13.   Vaccine companies say it normally takes years to develop and manufacture a vaccine.

14.   Having small quantities of dangerous agents for research purposes would make the institute no more threatening than an ordinary pharmaceutical factory manufacturing vaccines, he said.

15.   Iraq plans to refurbish a laboratory destroyed by U.N. weapons inspectors in order to manufacture vaccine for foot-and-mouth disease.

16.   Some are the same companies that spurned the U.S. Centers for Disease Control and Prevention when it was seeking a firm to manufacture smallpox vaccine.

17.   Drug companies are reluctant to begin trying to manufacture a vaccine before more is known about HIV.