11.   Its reduction by vascular endothelium and infiltrating mononuclear cells was greater in inflamed mucosa.

12.   The vascular endothelium seems to produce superoxide in the inflamed mucosa, which would exacerbate tissue injury in ulcerative colitis.

13.   We used the reduction of nitroblue tetrazolium to detect the generation of superoxide in inflamed colonic mucosa.

14.   Mononuclear cell clusters stained with formazan were found in inflamed mucosa only.

15.   Superoxide seems to be generated by the endothelium in inflamed colonic mucosa.

16.   As a result, the inflamed duodenal mucosa may then become susceptible to acid and this may ultimately lead to ulceration.

17.   Neutrophil accumulation in the inflamed intestinal mucosa is a prominent feature in ulcerative colitis.

18.   Previous investigators have also shown, by tissue extraction, an increased release of neutrophil granule constituents in the inflamed mucosa in ulcerative colitis.

19.   Two studies have shown that in inflammatory bowel disease the concentrations of arachidonic acid in the inflamed colonic mucosa were increased.

20.   Necropsy reveals a severely inflamed mucosa studded with yellowish-green purulent nodules.