101. He complained of increasing abdominal discomfort. 102. Five per cent complained of diarrhoea that resolved after a slight reduction of the bile acid medication. 103. No subject, however, complained of nausea or any other gastrointestinal tract symptoms at any time during the submaximal plateau. 104. One complained of diarrhoea and the other of abdominal discomfort and bloating. 105. All the patients had complained of chronic epigastric pain for years before diagnosis and eight had a past history of recurrent gastric ulcer, gastrointestinal bleeding, or gastritis. 106. During the course of the trial, one patient complained of regurgitation and another of diarrhoea, but in both cases these mild signs of intolerance occurred under placebo. 107. Three patients continued to complain of intermittent dysphagia suggestive of a motility disturbance and these changes are probably permanent. 108. In our study, significantly more miners complained of anorexia and weight loss than the general population, as shown in an earlier published report. 109. Twelve patients also complained of diarrhoea defined either as frequent passage of small amounts of stools or as habitual passage of liquid or semiliquid stools. 110. Nine patients with diarrhoea complained of incontinence in the presence of loose bowel movements only. |