91. Normally, a newly discovered substance must go through years of development and animal testing before it can move to human clinical trials. 92. NIH had supported the first two stages of human clinical trials. 93. No long-term human clinical trials have been conducted. 94. Now, patent in hand, Meloy would like Medtronic to sponsor human clinical trials of electro-stimulation to treat orgasmic disorders. 95. Only a few angiogenesis inhibitors have entered human trials. 96. Other angiogenesis inhibitors are already in early human trials, but none that have the potency exhibited by the angiostatin and endostatin. 97. Other companies with anti-sense drugs in human trials are Genta Inc. and Hybridon Inc. 98. Part way through the human trials, Gilead cut the dose of Adefovir in half to reduce possible kidney toxicity. 99. Part of that federal funding is even now set to launch the first human trial of a method for slowing the aging process. 100. Preliminary human trials last year showed the concept works with raw potatoes. |