1.   A culture of isolation and relentless profit pressure had taken its toll.

2.   Adventure Story was still taking its toll.

3.   All the long seasons ending with championship series, all the tough games, it takes a toll.

4.   And Katherine could do with all the comfort she could get for the illness was slowly and inexorably taking its toll.

5.   As for Mr Patrick, he says the fight over development has taken its toll.

6.   Bad working conditions eventually take a toll on staff morale.

7.   Balancing the dual roles of minister to the world and shepherd to his own flock has taken its toll.

8.   But things went downhill as the days went by-and the drudgery in much of the work took its toll.

9.   Constant use of hairdryers and heated rollers takes its toll.