1.   Often there is a family history of recurrent ulcers in the parents as well.

2.   The herpes simplex virus can also cause recurrent ulcers.

3.   In addition, gap junctions in patients with recurrent ulcer were significantly fewer than in those with first onset ulcer.

4.   The diagnosis of recurrent ulcers was made from the past history and gastrofibrescopic examination.

5.   The patients with recurrent ulcers had significantly fewer gap gunctions in the ulcer margin than did the patients with first onset ulcer.

6.   Interestingly, gap junctions in patients with recurrent ulcer were much fewer than in patients with first onset ulcer.

7.   Treatment failure was defined as evidence by endoscopy of a recurrent duodenal ulcer crater.